Have you been diagnosed with Parkinson's disease but are not taking medication?

What is the purpose of this study?

This study is designed to find ways to predict the progression and effective treatments for Parkinson's disease.

Can I participate in this study?

You may be eligible for this study if you meet the following criteria:

• Conditions:Parkinson Disease, PD, healthy control, biomarker, treatment
• Age: Between 30 - 100 Years
• Gender: Male or Female
• Inclusion Criteria:

  If you answer YES to the following questions, you may be eligible to participate in this study as a Parkinson's patient:
  
      1. Are you at least 30 years old?
      2. Have you had Parkinsons disease for less than 2 years?
  
  If you answer YES to the following questions, you may be eligible to participate in the study's control group (will not receive treatment):
  
      1. Are you at least 30 years old?
  
          *A study team member with discuss other criteria with you.
• Exclusion Criteria:

  If you answer YES to any the following questions you may not be eligible to participate in this study as a Parkinson's patient:
  
      1. Are you currently taking Parkinson's medications?
      2. Are you currently using anticoagulants (e.g., coumadin, heparin)?
  
  If you answer YES to any the following questions you may not be eligible to participate in the study's control group (will not receive treatment):
  
      1. Do you have a neurological disorder?
      2. Do you have a first degree relative with Parkinson's disease?
      2. Are you currently using anticoagulants (e.g., coumadin, heparin)?
  
          *A study team member with discuss other criteria with you.

Detail Study Description

The purpose of this study is to collect clinical information to help develop biomarkers for Parkinson’s disease. Biomarkers are proteins measured in blood whose concentration reflects presence or severity of a disease state. Finding biomarkers for Parkinson’s disease may be useful in developing new treatments. There will be no medication in this study. We will only collect information about the progression of your Parkinson's disease symptoms. If you decide to participate, you will be asked to come to Cleveland Clinic every 3 months for 1 year and once every 6 months for the next 2 to 4 years.

Study Treatments